Title: Anticancer effects of saponin and saponin–phospholipid complex of Panax notoginseng grown in Vietnam Authors: Dang Kim, T. Nguyen Thanh, H. Nguyen Thuy, D., (...) Boonsiri, P. Bui Thanh, T. Keywords: Antitumor;Breast cancer;Panax notoginseng;Saponin;Saponin–phospholipid complex Issue Date: 2016 Publisher: Hainan Medical University Citation: Scopus Abstract: Objective To evaluate the antitumor activity both in vitro and in vivo of saponin–phospholipid complex of Panax notoginseng. Methods The in vitro cytotoxic effect of saponins extract and saponin–phospholipid complex against human lung cancer NCI-H460 and breast cancer cell lines BT474 was examined using MTS assay. For in vivo evaluation of antitumor potential, saponin and saponin–phospholipid complex were administered orally in rats induced mammary carcinogenesis by 7,12-dimethylbenz(a)anthracene, for 30 days. Results Our data showed that saponin–phospholipid complex ha...
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